MAP3K2 anticorps (AA 1-364)

N° du produit ABIN7869256

Cet anticorps anti-MAP3K2 Polyclonal Lapin (ABIN7869256) détecte spécifiquement MAP3K2 dans WB, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour MAP3K2 anticorps (AA 1-364) (ABIN7869256)

Antigène: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP3K2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-MAP3K2 anticorps

Épitope: AA 1-364

Fonction: MEKK2 Antibody

Purification: Affinity purified

Immunogène: A human recombinant partial protein (amino acids M1-Q364) was used as the immunogen for the MEKK2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MEKK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MEKK2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MAP3K2

Antigène: MAP3K2 (Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2))

Autre désignation: MEKK2

Sujet: MAP3K2, mitogen-activated protein kinase kinase kinase 2, also known as MEKK2, belongs to the mitogen-activated protein kinase (MAPK) kinase kinase gene family, which is involved in regulating multiple MAPK signaling pathways. Endogenous MAP3K2 localized mainly to the cytosol of unstimulated HeLa cells and rat fibroblasts. The MAP3K2 gene is mapped to chromosome 2 by the International Radiation Hybrid Mapping Consortium. MAP3K2 is a major upstream activator of the JNK, MAPK cascade. MAP3K2 was identifies as 1 of 6 kinases that regulate different steps of the caveolar cycle. Silencing of MAP3K2 strongly reduced kiss-and-run dynamics, leading to an accumulation of caveolar structures at the cell surface without affecting caveolae coat assembly or clustering.

UniProt: Q9Y2U5

Pathways: Signalisation MAPK