Recombinant LEF1 anticorps (AA 1-399)

N° du produit ABIN7869301

Cet anticorps anti-LEF1 Monoclonal Souris (Clone rLEF1-8854) (ABIN7869301) détecte spécifiquement LEF1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant LEF1 anticorps (AA 1-399) (ABIN7869301)

Antigène: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LEF1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RLEF1-8854

Détail du produit anti-LEF1 anticorps

Épitope: AA 1-399

Fonction: LEF1 Antibody / Lymphoid enhancer-binding factor 1 / TCF alpha

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-399) from the human protein was used as the immunogen for the LEF1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the LEF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the LEF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur LEF1

Antigène: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Autre désignation: LEF1

Sujet: Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells.Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.

UniProt: Q9UJU2

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding