CAMK2A anticorps (AA 1-478)

N° du produit ABIN7869399

L’anticorps anti-CAMK2A Polyclonal Lapin est utilisé pour la détection de CAMK2A dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour CAMK2A anticorps (AA 1-478) (ABIN7869399)

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAMK2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-CAMK2A anticorps

Épitope: AA 1-478

Fonction: CAMK II alpha Antibody / CAMK2A

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids M1-H478) was used as the immunogen for the CAMK II alpha antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CAMK II alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CAMK II alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CAMK2A

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Autre désignation: CAMK II alpha

Sujet: Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMKIIa), a.k.a. Ca2+/calmodulin-dependent protein kinase II alpha, is a protein kinase (i.e., an enzyme which phosphorylates proteins) that in humans is encoded by the CAMK2A gene. It is mapped to 5q32. The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.

UniProt: Q9UQM7

Pathways: Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction