LIN7C anticorps (AA 1-73)

N° du produit ABIN7869540

L’anticorps anti-LIN7C Polyclonal Lapin est utilisé pour la détection de LIN7C dans des échantillons de Humain et Rat. Il a été validé pour WB, ELISA, IHC (p) et FACS.

Aperçu rapide pour LIN7C anticorps (AA 1-73) (ABIN7869540)

Antigène: LIN7C (Lin-7 Homolog C (LIN7C))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN7C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-LIN7C anticorps

Épitope: AA 1-73

Fonction: LIN7C Antibody / Protein lin-7 homolog C

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids M1-A73) was used as the immunogen for the LIN7C antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the LIN7C antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the LIN7C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur LIN7C

Antigène: LIN7C (Lin-7 Homolog C (LIN7C))

Autre désignation: LIN7C

Sujet: Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene. LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. It forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. LIN7C ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. It is also required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

UniProt: Q9NUP9

Pathways: Synaptic Membrane