S100A5 anticorps (AA 1-92)

N° du produit ABIN7869617

Cet anticorps Souris Monoclonal détecte spécifiquement S100A5 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour S100A5 anticorps (AA 1-92) (ABIN7869617)

Antigène: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp S100A5 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: S100A5-7474

Détail du produit anti-S100A5 anticorps

Épitope: AA 1-92

Fonction: S100A5 Antibody / S100 calcium binding protein A5

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-92) from the human protein was used as the immunogen for the S100A5 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the S100A5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the S100A5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur S100A5

Antigène: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Autre désignation: S100A5

Sujet: The S-100 proteins are small calcium-binding proteins which display different expression patterns in human tissues. Some S-100 proteins are associated with tumor development and the metastatic behavior of tumors. S-100A5 (S100 calcium binding protein A5) is a 92 amino acid protein that belongs to the S-100 family. Containing two EF-hand domains, S-100A5 binds calcium, zinc and copper. One subunit can simultaneously bind two calcium ions or two copper ions plus one zinc ion. Calcium and copper ions compete for the same binding sites on the S-100A5 protein. The S-100A5 protein is expressed in very restricted regions of the adult brain. The S-100A5 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 1q21.3. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Due to the clustered organization of the S-100 proteins a new logical nomenclature based on their physical arrangement on the chromosome has been described, with S-100A1 being closest to the telomere and S-100A9 being closest to the centromere.

UniProt: P33763

Pathways: S100 Proteins