Recombinant NKX2-8 anticorps (AA 10-123)

N° du produit ABIN7869674

Cet anticorps Lapin Monoclonal détecte spécifiquement NKX2-8 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant NKX2-8 anticorps (AA 10-123) (ABIN7869674)

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB)

Clone: NKX28-3233R

Détail du produit anti-NKX2-8 anticorps

Épitope: AA 10-123

Fonction: Recombinant NKX2.8 Antibody

Purification: Protein A affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 10-123) was used as the immunogen for the NKX2.8 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant NKX2.8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant NKX2.8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: NKX2.8

Sujet: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

UniProt: O15522