NKX2-8 anticorps (AA 10-123)

N° du produit ABIN7869678

L’anticorps anti-NKX2-8 Monoclonal Souris est utilisé pour la détection de NKX2-8 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour NKX2-8 anticorps (AA 10-123) (ABIN7869678)

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB)

Clone: NKX28-2547

Détail du produit anti-NKX2-8 anticorps

Épitope: AA 10-123

Fonction: NKX2.8 Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 10-123) was used as the immunogen for the NKX2.8 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the NKX2.8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the NKX2.8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: NKX2.8

Sujet: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

UniProt: O15522