L’anticorps anti-Phospholipase C delta 3 Polyclonal Lapin est utilisé pour la détection de Phospholipase C delta 3 dans des échantillons de Humain. Il a été validé pour WB, ELISA, FACS et IF.
PLCd3
Reactivité: Humain, Souris
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the PLC-delta-3 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the PLC-delta-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
Phospholipase C delta 3 (PLCd3)
Autre désignation
PLC-delta-3
Sujet
1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 is an enzyme that in humans is encoded by the PLCD3 gene. This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.