Amphiregulin anticorps (AA 101-180)

N° du produit ABIN7869891

L’anticorps anti-Amphiregulin Polyclonal Lapin est utilisé pour la détection de Amphiregulin dans des échantillons de Humain. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour Amphiregulin anticorps (AA 101-180) (ABIN7869891)

Antigène: Amphiregulin (AREG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amphiregulin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Amphiregulin anticorps

Épitope: AA 101-180

Fonction: AREG Antibody / Amphiregulin

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids S101-R180) was used as the immunogen for the AREG antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the AREG antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the AREG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Amphiregulin

Antigène: Amphiregulin (AREG)

Autre désignation: AREG

Sujet: Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage.

UniProt: P15514

Pathways: Signalisation RTK, EGFR Signaling Pathway