VEGFC anticorps (AA 108-223)

N° du produit ABIN7870024

Cet anticorps anti-VEGFC Polyclonal Lapin (ABIN7870024) détecte spécifiquement VEGFC dans WB et ELISA. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour VEGFC anticorps (AA 108-223) (ABIN7870024)

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEGFC est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-VEGFC anticorps

Épitope: AA 108-223

Fonction: Vegfc Antibody / Vascular endothelial growth factor C

Purification: Antigen affinity purified

Immunogène: An E.coli-derived mouse recombinant protein (A108-R223) was used as the immunogen for the Vegfc antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Vegfc antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Vegfc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur VEGFC

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Autre désignation: Vegfc

Sujet: Vascular endothelial growth factor C (VEGF-C) is a protein that is a member of the platelet-derived growth factor / vascular endothelial growth factor (PDGF/VEGF) family. It is encoded in humans by the VEGFC gene, which is located on chromosome 4q34. Enables vascular endothelial growth factor receptor 3 binding activity. Involved in several processes, including negative regulation of osteoblast differentiation, positive regulation of angiogenesis, and positive regulation of mesenchymal stem cell proliferation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor, positive regulation of lymphangiogenesis, and positive regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in several structures, including alimentary system mesentery, brain, cardiovascular system, embryo mesenchyme, and genitourinary system. Used to study hereditary lymphedema. Human ortholog(s) of this gene implicated in breast carcinoma and hereditary lymphedema ID. Orthologous to human VEGFC (vascular endothelial growth factor C).

UniProt: P97953

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2