Neurogranin anticorps (AA 11-54)

N° du produit ABIN7870089

L’anticorps anti-Neurogranin Polyclonal Lapin est utilisé pour la détection de Neurogranin dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour Neurogranin anticorps (AA 11-54) (ABIN7870089)

Antigène: Neurogranin (NRGN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurogranin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Neurogranin anticorps

Épitope: AA 11-54

Fonction: NRGN Antibody / Neurogranin

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids K11-K54) was used as the immunogen for the NRGN antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the NRGN antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the NRGN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Neurogranin

Antigène: Neurogranin (NRGN)

Autre désignation: NRGN

Sujet: Neurogranin is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

UniProt: Q92686