POLG anticorps (AA 1120-1148)

N° du produit ABIN7870144

Cet anticorps anti-POLG Polyclonal Lapin (ABIN7870144) détecte spécifiquement POLG dans WB, IHC (p), IF et FACS. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour POLG anticorps (AA 1120-1148) (ABIN7870144)

Antigène: POLG (Polymerase (DNA Directed), gamma (POLG))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-POLG anticorps

Épitope: AA 1120-1148

Fonction: POLG Antibody

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1120-1148 from the human protein was used as the immunogen for the POLG antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the POLG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the POLG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur POLG

Antigène: POLG (Polymerase (DNA Directed), gamma (POLG))

Autre désignation: POLG

Sujet: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

UniProt: P54098