Dystrophin anticorps (AA 114-263)

N° du produit ABIN7870179

L’anticorps anti-Dystrophin Monoclonal Souris est utilisé pour la détection de Dystrophin dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Dystrophin anticorps (AA 114-263) (ABIN7870179)

Antigène: Dystrophin (DMD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Dystrophin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: DSTN-1

Détail du produit anti-Dystrophin anticorps

Épitope: AA 114-263

Fonction: Dystrophin Antibody / DMD (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Amino acids 114-263 from the human protein were used as the immunogen for the Dystrophin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Dystrophin antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Dystrophin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Dystrophin

Antigène: Dystrophin (DMD)

Autre désignation: Dystrophin

Sujet: The DMD gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [RefSeq]

UniProt: P11532

Pathways: Skeletal Muscle Fiber Development