Recombinant TPSAB1 anticorps (AA 115-233)

N° du produit ABIN7870204

Cet anticorps anti-TPSAB1 Monoclonal Souris (Clone rTPSAB1-1963) (ABIN7870204) détecte spécifiquement TPSAB1 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant TPSAB1 anticorps (AA 115-233) (ABIN7870204)

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TPSAB1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RTPSAB1-1963

Détail du produit anti-TPSAB1 anticorps

Épitope: AA 115-233

Fonction: Recombinant TPSAB1 Antibody / Tryptase

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 115-233 from the human protein was used as the immunogen for this recombinant TPSAB1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant TPSAB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant TPSAB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur TPSAB1

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Autre désignation: TPSAB1

Sujet: Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.

UniProt: Q15661