TPSAB1 anticorps (AA 115-233)

N° du produit ABIN7870205

Cet anticorps Souris Monoclonal détecte spécifiquement TPSAB1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TPSAB1 anticorps (AA 115-233) (ABIN7870205)

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TPSAB1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: TPSAB1-1961

Détail du produit anti-TPSAB1 anticorps

Épitope: AA 115-233

Fonction: TPSAB1 Antibody / Mast Cell Tryptase (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 115-233 from the human protein was used as the immunogen for this TPSAB1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the TPSAB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TPSAB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur TPSAB1

Antigène: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Autre désignation: TPSAB1

Sujet: Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.

UniProt: Q15661