TRF1 anticorps (AA 119-341)
Aperçu rapide pour TRF1 anticorps (AA 119-341) (ABIN7870276)
Antigène
Voir toutes TRF1 (TERF1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 119-341
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Fonction
- Telomeric repeat-binding factor 1 Antibody / TRF1 / TERF1
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Purification
- Antigen affinity purified
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Immunogène
- Recombinant human protein (amino acids Q119-R341) was used as the immunogen for the Telomeric repeat-binding factor 1 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Telomeric repeat-binding factor 1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Telomeric repeat-binding factor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))
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Autre désignation
- Telomeric repeat-binding factor 1
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Sujet
- Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene. This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
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UniProt
- P54274
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Pathways
- Cycle Cellulaire, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity
Antigène
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