PFKFB1 anticorps (AA 12-186)

N° du produit ABIN7870283

Cet anticorps Lapin Polyclonal détecte spécifiquement PFKFB1 dans WB, ELISA, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PFKFB1 anticorps (AA 12-186) (ABIN7870283)

Antigène: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKFB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-PFKFB1 anticorps

Épitope: AA 12-186

Fonction: PFKFB1 Antibody / Fructose-2,6-bisphosphatase

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids R12-R186) was used as the immunogen for the PFKFB1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PFKFB1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PFKFB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PFKFB1

Antigène: PFKFB1 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1))

Autre désignation: PFKFB1

Sujet: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.

UniProt: P16118

Pathways: Regulation of Carbohydrate Metabolic Process