STRADA anticorps (AA 12-41)

N° du produit ABIN7870293

L’anticorps anti-STRADA Polyclonal Lapin est utilisé pour la détection de STRADA dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour STRADA anticorps (AA 12-41) (ABIN7870293)

Antigène: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STRADA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-STRADA anticorps

Épitope: AA 12-41

Fonction: LYK5 Antibody / STRADA

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 12-41 from the human protein was used as the immunogen for the LYK5 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the LYK5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the LYK5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur STRADA

Antigène: STRADA (STE20-Related Kinase Adaptor alpha (STRADA))

Autre désignation: LYK5

Sujet: LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.

UniProt: Q7RTN6

Pathways: AMPK Signaling