Sclerostin anticorps (AA 12-42)

N° du produit ABIN7870294

Cet anticorps anti-Sclerostin Polyclonal Lapin (ABIN7870294) détecte spécifiquement Sclerostin dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Sclerostin anticorps (AA 12-42) (ABIN7870294)

Antigène: Sclerostin (SOST)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sclerostin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Sclerostin anticorps

Épitope: AA 12-42

Fonction: Sclerostin Antibody / SOST

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 12-42 from the human protein was used as the immunogen for the Sclerostin antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Sclerostin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Sclerostin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Sclerostin

Antigène: Sclerostin (SOST)

Autre désignation: Sclerostin

Sujet: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

UniProt: Q9BQB4