MBD2 anticorps (AA 120-152)

N° du produit ABIN7870307

Cet anticorps Lapin Polyclonal détecte spécifiquement MBD2 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MBD2 anticorps (AA 120-152) (ABIN7870307)

Antigène: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MBD2 anticorps

Épitope: AA 120-152

Fonction: MBD2 Antibody / Methyl-CpG-binding domain protein 2

Purification: Antigen affinity

Immunogène: A portion of amino acids 120-152 from the human protein was used as the immunogen for the MBD2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the MBD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MBD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MBD2

Antigène: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Autre désignation: MBD2

Sujet: MBD2 is part of a family of proteins that possess a methyl-CpG-binding domain, allowing them to recognize and bind to DNA that has been modified by the addition of methyl groups. This binding has important implications for gene expression, as methylation can either activate or repress gene transcription. One of the most intriguing aspects of MBD2 is its ability to recruit other proteins to the methylated DNA, influencing the chromatin structure and ultimately determining whether a particular gene is switched on or off. This dynamic interplay between MBD2 and other regulatory proteins highlights the complexity of epigenetic regulation. Research into MBD2 has uncovered its involvement in a wide range of biological processes, from embryonic development to cancer progression. Dysregulation of MBD2 has been linked to aberrant gene expression patterns seen in various diseases, making it a potential target for therapeutic interventions.

Pathways: Chromatin Binding