TXNIP anticorps (AA 122-152)
Aperçu rapide pour TXNIP anticorps (AA 122-152) (ABIN7870330)
Antigène
Voir toutes TXNIP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 122-152
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Fonction
- Thioredoxin-interacting protein Antibody / TXNIP
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (amino acids D122-N152) was used as the immunogen for the Thioredoxin-interacting protein antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Thioredoxin-interacting protein antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the Thioredoxin-interacting protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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Autre désignation
- Thioredoxin-interacting protein
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Sujet
- Thioredoxin-interacting protein is a protein that in humans is encoded by the TXNIP gene. This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants.
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UniProt
- Q9H3M7
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Pathways
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
Antigène
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