BACE1 anticorps (AA 125-154)
Aperçu rapide pour BACE1 anticorps (AA 125-154) (ABIN7870373)
Antigène
Voir toutes BACE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 125-154
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Fonction
- Beta-secretase 1 Antibody / Memapsin-2 / BACE1C
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Purification
- Purified
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Immunogène
- A portion of amino acids 125-154 from the human protein was used as the immunogen for the Beta-secretase 1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the Beta-secretase 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the Beta-secretase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Autre désignation
- Beta-secretase 1
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Sujet
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
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UniProt
- P56817
Antigène
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