PGK1 anticorps (AA 138-337)

N° du produit ABIN7870590

L’anticorps anti-PGK1 Polyclonal Lapin est utilisé pour la détection de PGK1 dans des échantillons de Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC (p).

Aperçu rapide pour PGK1 anticorps (AA 138-337) (ABIN7870590)

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PGK1 anticorps

Épitope: AA 138-337

Fonction: Zebrafish Pgk1 Antibody / Phosphoglycerate kinase 1

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived zebrafish Pgk1 recombinant protein (amino acids N138-N337) was used as the immunogen for the Zebrafish Pgk1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Pgk1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Pgk1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PGK1

Antigène: PGK1 (Phosphoglycerate Kinase 1 (PGK1))

Autre désignation: Pgk1

Sujet: PGK1 (Phosphoglycerate Kinase 1), also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.

UniProt: Q7ZV29

Pathways: Cellular Glucan Metabolic Process