LEF1 anticorps (AA 14-274)

N° du produit ABIN7870624

Cet anticorps anti-LEF1 Polyclonal Lapin (ABIN7870624) détecte spécifiquement LEF1 dans WB, ELISA, IF et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LEF1 anticorps (AA 14-274) (ABIN7870624)

Antigène: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LEF1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-LEF1 anticorps

Épitope: AA 14-274

Fonction: TCF1 alpha Antibody / LEF1 / Lymphoid enhancer-binding factor 1

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids D14-H274) was used as the immunogen for the TCF1 alpha antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TCF1 alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TCF1 alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur LEF1

Antigène: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Autre désignation: TCF1 alpha

Sujet: Lymphoid enhancer-binding factor 1 (LEF1), also called T cell-specific transcription factor 1-alpha (TCF1 alpha) is a protein that in humans is encoded by the LEF1 gene. This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

UniProt: Q9UJU2

Pathways: Signalisation WNT, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding