FDFT1 anticorps (AA 140-170)

N° du produit ABIN7870661

Cet anticorps Lapin Polyclonal détecte spécifiquement FDFT1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FDFT1 anticorps (AA 140-170) (ABIN7870661)

Antigène: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDFT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FDFT1 anticorps

Épitope: AA 140-170

Fonction: Squalene synthase Antibody / SQS / FDFT1

Purification: Purified

Immunogène: A portion of amino acids 140-170 from the human protein was used as the immunogen for the Squalene synthase antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Squalene synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Squalene synthase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FDFT1

Antigène: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Autre désignation: Squalene synthase

Sujet: FDFT1 / Squalene synthase catalyzes the first step in the cholesterol biosynthetic pathway, the conversion of trans-farnesyldiphosphate to squalene. The loss of promoter activity and response to sterols for FDFT1 is localized to a 69-bp section positioned 131 bp 5-prime to the transcription start site. Sequence analysis of this region shows that it contains a sterol regulatory element-1 (SRE1) previously identified in other sterol regulated genes and 2 putative NF1 binding sites.

UniProt: P37268

Pathways: Regulation of Lipid Metabolism by PPARalpha