PGC anticorps (AA 145-356)

N° du produit ABIN7870725

L’anticorps anti-PGC Polyclonal Lapin est utilisé pour la détection de PGC dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA, IF, IHC (p) et FACS.

Aperçu rapide pour PGC anticorps (AA 145-356) (ABIN7870725)

Antigène: PGC (Pepsinogen C (PGC))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-PGC anticorps

Épitope: AA 145-356

Fonction: PGC Antibody

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids Y145-N356) was used as the immunogen for the PGC antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PGC antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PGC Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PGC

Antigène: PGC (Pepsinogen C (PGC))

Autre désignation: PGC

Sujet: Progastricsin also known as pepsinogen C or pepsinogen II is a pepsinogen precursor of the enzyme gastricsin that in humans is encoded by the PGC gene. This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

UniProt: P20142