Cet anticorps anti-POU2AF1 Monoclonal Souris (Clone BOB1-2425) (ABIN7870765) détecte spécifiquement POU2AF1 dans WB et IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
Optimal dilution of the BOB1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the BOB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Antigène
POU2AF1
(POU Class 2 Associating Factor 1 (POU2AF1))
Autre désignation
BOB1
Sujet
BOB1, also called POU2AF1, expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.