L’anticorps anti-POU2AF1 Monoclonal Souris est utilisé pour la détection de POU2AF1 dans des échantillons de Humain. Il a été validé pour WB, FACS, IHC (p) et IF.
Optimal dilution of the BOB-1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
4 °C,-20 °C
Stockage commentaire
Store the BOB-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Antigène
POU2AF1
(POU Class 2 Associating Factor 1 (POU2AF1))
Autre désignation
BOB-1
Sujet
BOB-1, also called POU2AF1, expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB-1. Conversely, only some cases of classical Hodgkin lymphoma show BOB-1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB-1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.