POT1 anticorps (AA 15-638)
Aperçu rapide pour POT1 anticorps (AA 15-638) (ABIN7870800)
Antigène
Voir toutes POT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 15-638
-
Fonction
- POT1 Antibody
-
Purification
- Affinity purified
-
Immunogène
- Recombinant rat protein (amino acids N15-V638) was used as the immunogen for the POT1 antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the POT1 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- After reconstitution, the POT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- POT1 (Protection of Telomeres 1 (POT1))
-
Autre désignation
- POT1
-
Sujet
- Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
-
Pathways
- Cycle Cellulaire, Telomere Maintenance
Antigène
-