Recombinant Prostate Specific Antigen anticorps (AA 150-250)

N° du produit ABIN7870871

Cet anticorps Lapin Monoclonal détecte spécifiquement Prostate Specific Antigen dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Prostate Specific Antigen anticorps (AA 150-250) (ABIN7870871)

Antigène: Prostate Specific Antigen (PSA)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Prostate Specific Antigen est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KLK3-4602R

Détail du produit anti-Prostate Specific Antigen anticorps

Épitope: AA 150-250

Fonction: Recombinant PSA Antibody / Prostate Specific Antigen

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 150-250 of Prostate-specific antigen protein was used as the immunogen for the recombinant PSA antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the recombinant PSA antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant PSA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Prostate Specific Antigen

Antigène: Prostate Specific Antigen (PSA)

Autre désignation: PSA

Sujet: Prostate-specific antigen (PSA) is a single-chain glycoprotein of 237 amino acids containing approximately 8 % carbohydrate. It is a serine protease produced almost exclusively by prostatic epithelial cells. Immunohistochemically PSA is expressed in the highly specialized apically-superficial layer of female and male secretory cells of the prostate gland, and is readily demonstrated in adenocarcinomas of the prostate in about 99 % of the cases. There is a correlation between malignancy grade and intensity of staining, high grade carcinomas displaying weaker expression. About 1 % of poorly differentiated carcinomas have been negative for PSA. Due to the high specificity of PSA for prostatic glandular epithelium, it is very useful in identifying prostatic carcinoma in the prostate and in the adjacent organs often affected by epithelial malignancies, i.e. rectum and urinary bladder. PSA may be used in a panel together with NKX3.1 and Prostein, which are at least as sensitive and slightly more specific than PSA.

UniProt: P07288

Pathways: Système du Complément