DBN1 anticorps (AA 150-281)

N° du produit ABIN7870875

L’anticorps anti-DBN1 Monoclonal Souris est utilisé pour la détection de DBN1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour DBN1 anticorps (AA 150-281) (ABIN7870875)

Antigène: DBN1 (Drebrin 1 (DBN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DBN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DBN1-2879

Détail du produit anti-DBN1 anticorps

Épitope: AA 150-281

Fonction: Drebrin 1 Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 150-281) was used as the immunogen for the Drebrin 1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Drebrin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Drebrin 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur DBN1

Antigène: DBN1 (Drebrin 1 (DBN1))

Autre désignation: Drebrin 1

Sujet: Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.

UniProt: Q16643

Pathways: Maintenance of Protein Location