BAI1 anticorps (AA 1537-1567)

N° du produit ABIN7870991

Cet anticorps Lapin Polyclonal détecte spécifiquement BAI1 dans WB, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour BAI1 anticorps (AA 1537-1567) (ABIN7870991)

Antigène: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAI1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-BAI1 anticorps

Épitope: AA 1537-1567

Fonction: Brain-specific angiogenesis inhibitor 1 Antibody / BAI1

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1537-1567 from the human protein was used as the immunogen for the Brain-specific angiogenesis inhibitor 1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Brain-specific angiogenesis inhibitor 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Brain-specific angiogenesis inhibitor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur BAI1

Antigène: BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))

Autre désignation: Brain-specific angiogenesis inhibitor 1

Sujet: Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.

UniProt: O14514

Pathways: Signalisation p53