RAB7A anticorps (AA 156-197)
Aperçu rapide pour RAB7A anticorps (AA 156-197) (ABIN7871017)
Antigène
Voir toutes RAB7A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 156-197
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Fonction
- RAB7A Antibody
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Purification
- Antigen affinity purified
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Immunogène
- An E.coli-derived human recombinant protein (A156-R197) was used as the immunogen for the RAB7A antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the RAB7A antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the RAB7A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RAB7A (RAB7A, Member RAS Oncogene Family (RAB7A))
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Autre désignation
- RAB7A
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Sujet
- Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.
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UniProt
- P51149
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Pathways
- EGFR Signaling Pathway, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome
Antigène
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