SNIP1
Reactivité: Humain
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
Cy3
Indications d'application
Optimal dilution of the SNIP1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the SNIP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
SNIP1
(Smad Nuclear Interacting Protein 1 (SNIP1))
Autre désignation
SNIP1
Sujet
Smad nuclear-interacting protein 1 is a protein that in humans is encoded by the SNIP1 gene. This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).