Neurofibromin 1 anticorps (AA 160-270)

N° du produit ABIN7871100

L’anticorps anti-Neurofibromin 1 Monoclonal Souris est utilisé pour la détection de Neurofibromin 1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF, IHC (p) et FACS.

Aperçu rapide pour Neurofibromin 1 anticorps (AA 160-270) (ABIN7871100)

Antigène: Neurofibromin 1 (NF1)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neurofibromin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 4F8B7

Détail du produit anti-Neurofibromin 1 anticorps

Épitope: AA 160-270

Fonction: NF1 Antibody / Neurofibromin

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids R160-Q270) was used as the immunogen for the NF1 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the NF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the NF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: NF1

Sujet: Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

UniProt: P21359

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity