Neurofibromin 1 anticorps (AA 160-270)

N° du produit ABIN7871101

Cet anticorps anti-Neurofibromin 1 Monoclonal Souris (Clone 4C6F10) (ABIN7871101) détecte spécifiquement Neurofibromin 1 dans WB, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Neurofibromin 1 anticorps (AA 160-270) (ABIN7871101)

Antigène: Neurofibromin 1 (NF1)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Neurofibromin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 4C6F10

Détail du produit anti-Neurofibromin 1 anticorps

Épitope: AA 160-270

Fonction: Neurofibromin Antibody / NF1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids R160-Q270) was used as the immunogen for the Neurofibromin antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Neurofibromin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Neurofibromin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Neurofibromin 1

Antigène: Neurofibromin 1 (NF1)

Autre désignation: Neurofibromin

Sujet: Neurofibromin 1 (NF1) is a gene in humans that is located on chromosome 17. This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

UniProt: P21359

Pathways: cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity