TLN1 anticorps (AA 1658-1876)

N° du produit ABIN7871151

L’anticorps anti-TLN1 Monoclonal Souris est utilisé pour la détection de TLN1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et FACS.

Aperçu rapide pour TLN1 anticorps (AA 1658-1876) (ABIN7871151)

Antigène: TLN1 (Talin 1 (TLN1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLN1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 2G10D2

Détail du produit anti-TLN1 anticorps

Épitope: AA 1658-1876

Fonction: TLN1 Antibody / Talin 1

Purification: Antigen affinity purified

Immunogène: Recombinant human Talin 1/TLN1 protein (amino acids Q1658-N1876) was used as the immunogen for the TLN1 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the TLN1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TLN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TLN1

Antigène: TLN1 (Talin 1 (TLN1))

Autre désignation: TLN1

Sujet: Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location