Hexokinase 1 anticorps (AA 17-323)

N° du produit ABIN7871222

Cet anticorps Souris Monoclonal détecte spécifiquement Hexokinase 1 dans WB, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Hexokinase 1 anticorps (AA 17-323) (ABIN7871222)

Antigène: Hexokinase 1 (HK1)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Hexokinase 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 4B7

Détail du produit anti-Hexokinase 1 anticorps

Épitope: AA 17-323

Fonction: HK1 Antibody / Hexokinase 1

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids D17-R323) was used as the immunogen for the HK1 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the HK1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Hexokinase 1

Antigène: Hexokinase 1 (HK1)

Autre désignation: HK1

Sujet: Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. It is mapped to 10q22.1. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

UniProt: P19367

Pathways: Carbohydrate Homeostasis, L'effet Warburg