Reelin anticorps (AA 1796-2115)

N° du produit ABIN7871362

Cet anticorps anti-Reelin Monoclonal Souris (Clone RELN-4498) (ABIN7871362) détecte spécifiquement Reelin dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Reelin anticorps (AA 1796-2115) (ABIN7871362)

Antigène: Reelin (RELN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Reelin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: RELN-4498

Détail du produit anti-Reelin anticorps

Épitope: AA 1796-2115

Fonction: Reelin Antibody / RELN (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 1796-2115 was used as the immunogen for the Reelin antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Reelin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Reelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Reelin

Antigène: Reelin (RELN)

Autre désignation: Reelin

Sujet: Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

UniProt: P78509

Pathways: Synaptic Membrane