Reelin anticorps (AA 1796-2115)

N° du produit ABIN7871363

Cet anticorps Souris Monoclonal détecte spécifiquement Reelin dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Reelin anticorps (AA 1796-2115) (ABIN7871363)

Antigène: Reelin (RELN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Reelin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RELN-4498

Détail du produit anti-Reelin anticorps

Épitope: AA 1796-2115

Fonction: Reelin Antibody / RELN

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 1796-2115 was used as the immunogen for the Reelin antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the Reelin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Reelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Reelin

Antigène: Reelin (RELN)

Autre désignation: Reelin

Sujet: Reelin (or Reln) is a large glycoprotein that is secreted by Cajal-Retzius cells in the forebrain and by granule neurons in the cerebellum. Reelin was shown to be mutated in reeler mice, a mutation that is associated with widespread disruption of laminated regions of the brain, leading to impaired motor coordination, tremors and ataxia. Reelin protein expression is complex and changes throughout development. Reelin appears to function upstream of Dab1, in a signaling pathway that controls cell positioning in the developing brain, and is also thought to be a direct effector of the neurotrophin BDNF.

UniProt: P78509

Pathways: Synaptic Membrane