MUTYH anticorps (AA 187-528)

N° du produit ABIN7871513

Cet anticorps Lapin Polyclonal détecte spécifiquement MUTYH dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour MUTYH anticorps (AA 187-528) (ABIN7871513)

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUTYH est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-MUTYH anticorps

Épitope: AA 187-528

Fonction: MUTYH Antibody / Adenine DNA glycosylase / MYH1

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids A187-N528) was used as the immunogen for the MUTYH antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MUTYH antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MUTYH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MUTYH

Antigène: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Autre désignation: MUTYH

Sujet: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9UIF7

Pathways: Réparation de l'ADN