FKBP15 anticorps (AA 19-1210)

N° du produit ABIN7871554

Cet anticorps anti-FKBP15 Polyclonal Lapin (ABIN7871554) détecte spécifiquement FKBP15 dans WB, ELISA, IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour FKBP15 anticorps (AA 19-1210) (ABIN7871554)

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP15 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-FKBP15 anticorps

Épitope: AA 19-1210

Fonction: FKBP15 Antibody / FKBP133

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids A19-D1210) was used as the immunogen for the FKBP15 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the FKBP15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the FKBP15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur FKBP15

Antigène: FKBP15 (FK506 Binding Protein 15, 133kDa (FKBP15))

Autre désignation: FKBP15

Sujet: FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, a group of proteins initially identified as immunophilins, targets for the immunosupressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a domain similar to Wiskott-Aldrich syndrome protein homology region 1 (WH1) in addition to the FK506-binding protein motif. FKBP15 is distributed along the axonal shafts and partially co-localizes with F-actin in the growth cones of dorsal root ganglion neurons, overexpression of FKBP15 resulted in the number of filopodia in transfected neurons, suggesting that FKBP15 modulates growth cone behavior. FKBP15 has also been shown to associate with both microtubules and the actin filament systems and disruption of its expression by RNAi resulted in delayed transport of early endosomes in HeLa cells indicating that FKBP15 is also involved in the transport of early endosomes. At least three isoforms of FKBP15 are known to exist.

UniProt: Q5T1M5

Pathways: SARS-CoV-2 Protein Interactome