ARID1A anticorps (AA 1900-2000)

N° du produit ABIN7871649

L’anticorps anti-ARID1A Monoclonal Souris est utilisé pour la détection de ARID1A dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour ARID1A anticorps (AA 1900-2000) (ABIN7871649)

Antigène: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARID1A est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ARID1A-7735

Détail du produit anti-ARID1A anticorps

Épitope: AA 1900-2000

Fonction: ARID1A Antibody

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1900-2000) from the human protein was used as the immunogen for the ARID1A antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the ARID1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ARID1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ARID1A

Antigène: ARID1A (AT Rich Interactive Domain 1A (SWI-Like) (ARID1A))

Autre désignation: ARID1A

Sujet: The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles.

UniProt: O14497

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Tube Formation