ERCC1 anticorps (AA 191-281)

N° du produit ABIN7871654

Cet anticorps Souris Monoclonal détecte spécifiquement ERCC1 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ERCC1 anticorps (AA 191-281) (ABIN7871654)

Antigène: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERCC1 est non-conjugé

Application: ELISA

Classe de qualité: Carrier-free

Clone: ERCC1-2318

Détail du produit anti-ERCC1 anticorps

Épitope: AA 191-281

Fonction: ERCC1 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 191-281 was used as the immunogen for the ERCC1 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the ERCC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the ERCC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur ERCC1

Antigène: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Autre désignation: ERCC1

Sujet: Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.

UniProt: P07992

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response