L’anticorps anti-TMEM255B Polyclonal Lapin est utilisé pour la détection de TMEM255B dans des échantillons de Souris et Rat. Il a été validé pour ELISA, WB et IHC (p).
TMEM255B
Reactivité: Humain
ELISA
Hôte: Lapin
Polyclonal
FITC
Indications d'application
Optimal dilution of the Fam70b antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the Fam70b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
TMEM255B
(Transmembrane Protein 255B (TMEM255B))
Autre désignation
Fam70b
Sujet
FAM70B (family with sequence similarity 70, member B) is a 326 amino acid membrane protein that belongs to the FAM70 family. The gene that encodes FAM70B maps to human chromosome 13, which contains around 114 million base pairs and encodes roughly 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.