TCL1A anticorps (AA 2-109)

N° du produit ABIN7871768

Cet anticorps Souris Monoclonal détecte spécifiquement TCL1A dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TCL1A anticorps (AA 2-109) (ABIN7871768)

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCL1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TCL1-2079

Détail du produit anti-TCL1A anticorps

Épitope: AA 2-109

Fonction: TCL1 Antibody

Purification: Protein G affinity chromatography

Immunogène: A portion of amino acids 2-109 from the human protein was used as the immunogen for the TCL1 antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal dilution of the TCL1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TCL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur TCL1A

Antigène: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Autre désignation: TCL1

Sujet: T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

UniProt: P56279

Pathways: Stem Cell Maintenance