PNN anticorps (AA 2-241)

N° du produit ABIN7871787

L’anticorps anti-PNN Polyclonal Lapin est utilisé pour la détection de PNN dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et FACS.

Aperçu rapide pour PNN anticorps (AA 2-241) (ABIN7871787)

Antigène: PNN (Pinin, Desmosome Associated Protein (PNN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PNN est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PNN anticorps

Épitope: AA 2-241

Fonction: Pinin Antibody / PNN / DRSP

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids A2-L241) was used as the immunogen for the Pinin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Pinin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Pinin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PNN

Antigène: PNN (Pinin, Desmosome Associated Protein (PNN))

Autre désignation: Pinin

Sujet: Pinin is a protein that in humans is encoded by the PNN gene. By yeast 2-hybrid analysis of HeLa cells, followed by sequence analysis, it was found that epitope-tagged human PNN interacted with the serine/arginine (SR)-rich proteins SRP75/SRSF4, SRM300/SRRM2, and SRRP130/PNISR. Truncation analysis revealed that the polyserine/RS domain of PNN and flanking sequences participated in binding to these SR proteins. The 4 proteins colocalized in the nucleus of HCE-T cells, and overexpression of any of these proteins affected the distribution of the others between nuclear speckles and nucleoplasm.

UniProt: Q9H307