IDO2 anticorps (AA 200-350)

N° du produit ABIN7871973

L’anticorps anti-IDO2 Monoclonal Souris est utilisé pour la détection de IDO2 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour IDO2 anticorps (AA 200-350) (ABIN7871973)

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IDO2-2638

Détail du produit anti-IDO2 anticorps

Épitope: AA 200-350

Fonction: INDOL1 Antibody / IDO2

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 200-350 was used as the immunogen for the INDOL1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the INDOL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the INDOL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur IDO2

Antigène: IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

Autre désignation: INDOL1

Sujet: IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.

UniProt: Q6ZQW0