MERTK anticorps (AA 21-489)

N° du produit ABIN7872177

L’anticorps anti-MERTK Polyclonal Lapin est utilisé pour la détection de MERTK dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, FACS et IHC (p).

Aperçu rapide pour MERTK anticorps (AA 21-489) (ABIN7872177)

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MERTK est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MERTK anticorps

Épitope: AA 21-489

Fonction: MerTK Antibody

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids A21-A489) was used as the immunogen for the MerTK antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MerTK antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MerTK antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MERTK

Antigène: MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))

Autre désignation: MerTK

Sujet: Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type(immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. This gene is also very important in inhibition of Toll-like receptors(TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

UniProt: Q12866

Pathways: Signalisation RTK