FCN3 anticorps (AA 214-243)

N° du produit ABIN7872226

Cet anticorps anti-FCN3 Polyclonal Lapin (ABIN7872226) détecte spécifiquement FCN3 dans WB, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FCN3 anticorps (AA 214-243) (ABIN7872226)

Antigène: FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCN3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-FCN3 anticorps

Épitope: AA 214-243

Fonction: Ficolin 3 Antibody / FCN3

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 214-243 from the human protein was used as the immunogen for the Ficolin 3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Ficolin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Ficolin 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FCN3

Antigène: FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))

Autre désignation: Ficolin 3

Sujet: Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.

UniProt: O75636

Pathways: Système du Complément